KMID : 0032220090210020185
|
|
Annals of Dermatology 2009 Volume.21 No. 2 p.185 ~ p.188
|
|
Progression from Acral Lentiginous Melanoma in situ to Invasive Acral Lentiginous Melanoma
|
|
Bae Jung-Min
Kim Hyung-Ok Park Young-Min
|
|
Abstract
|
|
|
Acral lentiginous melanoma (ALM) is the most common type of cutaneous melanoma in Asians. The very early stage of ALM demonstrates only a proliferation of a few atypical melanocytes within the epidermis, and has been termed ALM in situ. A 74-year-old male patient presented with a pigmented lesion on the left great toe for 12 years, which had initially showed only a few scattered hyperplastic atypical melanocytes without dermal invasion upon biopsy 5 years ago. This time however, rebiopsy of the lesion confirmed a diagnosis of ALM, stage IIIB. It could be inferred that the lesion had slowly progressed from ALM in situ to invasive ALM over a period of 12 years. Herein we report a case of ALM in situ which progressed to invasive ALM over a long period of time. We expect this report may assist physicians in early recognition and proper management of future cases of ALM in situ.
|
|
KEYWORD
|
|
Acral Lentiginous melanoma in situ
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|