KMID : 0043320080310080999
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Archives of Pharmacal Research 2008 Volume.31 No. 8 p.999 ~ p.1003
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New Butyrylcholinesterase Inhibitory Steroid and Peroxy Acid from Leucas urticifolia
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Fatima Itrat
Ahmad Ijaz Anis Itrat Malik Abdul Afza Nighat Iqbal Lubna Latif Mehreen
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Abstract
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A new steroid leucisterol (1) and a new peroxy acid urticic acid (2) along with methoxybenzyl benzoate (3), 4-hydroxy benzoic acid (4), -sitosterol (5), and ursolic acid (6), have been isolated from the chloroform soluble fraction of the whole plant of Leucas urticifolia. Their structures were elucidated on the basis of nuclear magnetic resonance (1D and 2D NMR) spectral data. Leucisterol showed potent inhibitory activity against butyrylcholinesterase enzyme.
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KEYWORD
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Leucas urticifloia, Labiatae, Leucisterol, Urticic acid, Butyrylcholinesterase inhibition
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