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KMID : 0213520060200040241
Korean Journal of Ophthalmology
2006 Volume.20 No. 4 p.241 ~ p.245
A Case of Inadvertent Anterior Chamber and Corneal Stromal Injection with Antibiotics during Cataract Operation
Ha Byoung-Jin

Lee Sang-Hyup
Kim Yong-Min
Kwon Hyun-Seok
Chu Young-Kwang
Seo Kyoung-Yul
Abstract
Purpose: To report a case of inadvertent anterior chamber and cornea stromal injection with high dose antibiotics and steroids during cataract operation.

Methods: During cataract operation on a 78 year-old female patient, high dose gentamicin (20 mg/0.5 ml) and dexamethasone (2 mg/0.5 ml) were inadvertently injected into the anterior chamber and cornea stroma when making cornea edema for sealing of the incision sites. Anterior chamber irrigation with balanced salt solution (BSS) was immediately administered. On postoperative day one, extensive cornea edema was noted, and best-corrected visual acuity was 0.2. Descemet¡¯s membrane folds were observed around the corneal incision sites. Topical 5% NaCl and 1% prednisolone were started.

Results: Four weeks postoperatively, corneal edema began to reduce significantly. At four months postoperatively, corneal edema fully resolved, and best-corrected visual acuity was 0.8. However, some Descemet¡¯s membrane folds still remained, and a decrease in the number of endothelial cells was noted by specular microscope.

Conclusion: In this case involving anterior chamber and cornea stromal injection with high dose antibiotics and steroids, immediate anterior chamber irrigation with balanced salt solution seemed an appropriate management, and the patient¡¯s long-term visual acuity appears good. To prevent such mistakes, precise labeling of all solutions and use of different syringe needles should be considered. Korean Journal of Ophthalmology 20(4):241-245, 2006
KEYWORD
Antibiotics, Balanced salt solution, Corneal edema
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