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KMID : 0213520090230020104
Korean Journal of Ophthalmology
2009 Volume.23 No. 2 p.104 ~ p.107
Primary Sebaceous Carcinoma of the Corneaoscleral Limbus With Pagetoid Recurrence
Park Sang-Jun

Wee Won-Ryang
Lee Jin-Hak
Kim Mee-Kum
Abstract
We report a sebaceous carcinoma confined to the corneoscleral limbus without involvement of the eyelid. A 60-year-old man, who showed multiple masses on the corneaoscleral limbus and limbal ulceration but with normal eyelids, underwent surgical en-bloc excision of the masses. Histopathologic examination revealed a sebaceous carcinoma. Three weeks after excision, multiple pagetoid recurrences were found along the bulbar conjunctiva 2 mm away from the limbus. After the application of topical mitomycin C, the pagetoid spread regressed completely. After a 2 year follow-up, no other local or systemic recurrences were observed. This report shows that the ulcerative mass which is confined to only the corneoscleral limbus may be a sebaceous carcinoma even without eyelid involvement. Topical mitomycin C may be effective for treating pagetoid spread of sebaceous carcinoma of limbal origin.
KEYWORD
Sebaceous carcinoma, Limbus, Conjunctiva, Pagetoid recurrence, Mitomycin C
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