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KMID : 0213520090230020112
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Korean Journal of Ophthalmology
2009 Volume.23 No. 2 p.112 ~ p.113
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A Case of Vogt-Koyanagi-Harada Disease in a Patient With Graves Disease
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Seo Je-Hyun
Yu Hyeong-Gon
Chung Hum
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Abstract
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A case of Vogt-Koyanagi-Harada disease (VKH) that developed in a 36-year-old woman with Graves’ disease was described. The patient was treated with Lugol’s solution and presented with bilateral serous retinal detachment. She had also suffered from methimazole-induced hypersensitivity and steroid-induced myopathy. Fluorescein angiography showed multiple leakage points and a lumbar puncture revealed pleocytosis, which was compatible with VKH. High dose steroid pulse therapy was successful. Altered immune regulation associated with drug-induced hypersensitivity may contribute to the development of VKH in patients with Graves’ disease.
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KEYWORD
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Drug-induced hypersensitivity, Graves’ disease, Hyperthyroidism, Iodine therapy, Vogt-Koyanagi-Harada disease
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