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KMID : 0213520100240030139
Korean Journal of Ophthalmology
2010 Volume.24 No. 3 p.139 ~ p.142
Evaluation of Corneal Biomechanical Properties Following Penetrating Keratoplasty Using the Ocular Response Analyzer
Shin Joo-Young

Choi Jin-Seok
Oh Joo-Youn
Kim Mee-Kum
Lee Jin-Hak
Wee Won-Ryang
Abstract
Purpose: To evaluate corneal biomechanical properties in eyes that had previously undergone penetrating keratoplasty (PK) using the ocular response analyzer (ORA).

Methods: We recruited 26 patients who had received unilateral PK. Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and cornea-compensated intraocular pressure (IOPcc) were measured with the ORA and were compared to the measurements from the contralateral eyes that did not undergo PK.

Results: The CH was 8.95¡¾2.59 mmHg in eyes that underwent PK and 9.78¡¾1.45 mmHg in the contralateral eyes that did not undergo PK (p=0.077). The CRF was 10.26¡¾2.64 mmHg in post-PK eyes and 9.75¡¾1.45 mmHg in the contralateral eyes (p=0.509), and the CH-CRF was significantly smaller in post-PK eyes (-1.31¡¾2.32 mmHg in post-PK eyes vs. 0.03¡¾0.88 mmHg in fellow eyes, p=0.016). The IOPg and IOPcc were significantly higher in the PK group than they were in the control group. The IOPcc¡¯s were 20.81¡¾7.81 mmHg and 16.27¡¾2.49 mmHg in post-PK and control eyes, respectively (p=0.011); and the IOPg¡¯s were 19.22¡¾7.34 mmHg and 15.07¡¾3.03 mmHg in post-PK and control eyes, respectively (p=0.019). The IOPcc-g¡¯s were 1.59¡¾2.81 mmHg and 1.21¡¾1.30 mmHg in post-PK and control eyes, respectively (p=0.412), and the central corneal thickness (CCT)¡¯s were 489.11¡¾90.60 ¥ìm and 556.24¡¾42.84 ¥ìm in post-PK and control eyes, respectively (p=0.068).

Conclusions: Following PK, CH tended to decrease while CRF tended to increase, significantly decreasing CH-CRF. A significantly higher intraocular pressure and a thinner CCT following PK may have contributed to the observed changes in these corneal biomechanical parameters.
KEYWORD
Cornea, Intraocular pressure, Penetrating keratoplasty
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