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KMID : 0213520100240040256
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Korean Journal of Ophthalmology
2010 Volume.24 No. 4 p.256 ~ p.259
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Optic Neuropathy Associated with Castleman Disease
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Kim Ung-Soo
Hwang Jeong-Min
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Abstract
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A 44-year-old woman with Castleman disease presented with acute visual loss in the left eye. A full ophthalmologic examination and imaging were performed. Visual acuity was 20/20 in the right eye and 20/100 in the left eye. Total dyschromatopsia, a relative afferent pupillary defect, and a cecocentral scotoma were observed in the left eye. Mild disc edema, without leaking during fluorescein angiography, was also observed. Magnetic resonance imaging revealed a small cystic epidermoid-like lesion in the right prepontine and suprasellar cistern. Her visual acuity did not improve and deteriorated to 20/200 in the left eye at 22 months after the initial visual loss. Optic neuropathy may rarely be associated with Castleman disease and suggests a poor prognosis.
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KEYWORD
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Castleman disease, Giant lymph node hyperplasia, Optic nerve diseases
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