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KMID : 0213520110250040275
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Korean Journal of Ophthalmology
2011 Volume.25 No. 4 p.275 ~ p.277
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A Case of Necrotizing Keratoscleritis in Primary Sjogren’s Syndrome
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Choi Won
Lee Shin-Seok
Park Yeong-Geol
Yoon Kyung-Chul
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Abstract
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We report on a case of necrotizing keratoscleritis in primary Sjogren’s syndrome. A 66-year-old female patient who was complaining of ocular pain, tearing and decreased vision in her right eye for the previous two days was admitted to our hospital. Visual acuity in the right eye was hand movement, and initial examination showed a 3.0 × 1.8 mm uveal mass bulging through a corneoscleral melting site in the nasal region of the right eye. Positive anti-nuclear antibody was identified at a titer of 1:320 with a speckled pattern, and both Sjogren’s syndrome A and Sjogren’s syndrome B antibody tests were positive, with titers >200 U/mL. A technetium 99m pertechnetate salivary scan revealed chronic sialoadenitis in the submandibular glands. We diagnosed the lesion as necrotizing keratoscleritis due to primary Sjogren’s syndrome. A corneoscleral patch graft was performed, followed by immunosuppression including oral cyclosporin and topical prednisolone. During a follow-up period of 12 months, the corneoscleral graft was well maintained with no recurrence.
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KEYWORD
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Immunosuppression, Necrotizing scleritis, Sjogren’s syndrome
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