|
KMID : 0213520130270020087
|
|
Korean Journal of Ophthalmology
2013 Volume.27 No. 2 p.87 ~ p.92
|
|
|
Effects of a Novel Push-through Technique Using the Implantable Collamer Lens Injector System for Graft Delivery during Endothelial Keratoplasty
|
|
Kang Sug-Jae
Kim Myung-Hun
Kim Mee-Kum
Wee Won-Ryang
Lee Jin-Hak
Chung Eui-Sang
|
|
|
Abstract
|
|
|
Purpose: To investigate effects of a new push-through insertion method for donor lenticules using an injector system on endothelial viability ex vivo and in a clinical case series of endothelial keratoplasty.
Methods: An ex vivo delivery model was used with porcine corneoscleral rims. We compared the endothelial viability in a new push-through insertion method using the Visian Implantable Collamer Lens (ICL) injector versus that of standard forceps-assisted insertion for lenticule delivery. Twenty porcine corneal lenticules were divided into four groups by insertion method and wound size. Vital dye staining was performed and devitalized areas were semi-quantitatively assessed by digital imaging. In the clinical case series, Descemet’s stripping endothelial keratoplasty (DSEK) using the push-through method was performed in seven patients and endothelial outcome was determined six months postoperatively.
Results: Mean devitalized areas for the push-through method were significantly lower than for forceps-assisted insertion through 3.2 mm incision (23.99 ± 2.17% vs. 50.48 ± 5.07%, p = 0.009) in the ex vivo model. Average endothelial cell counts of donor tissues of patients who underwent DSEK were 26.4% lower six months postoperatively.
Conclusions: Push-through delivery of donor lenticules using the Visian ICL injector system appears to be less harmful to endothelial cells than conventional forceps-assisted delivery.
|
|
|
KEYWORD
|
|
|
Descemet’s stripping endothelial keratoplasty, Endothelial viability, Visian implantable collamer lens injector system
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|