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KMID : 0213520130270030158
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Korean Journal of Ophthalmology
2013 Volume.27 No. 3 p.158 ~ p.161
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Evaluation of Plasma Vitamin A and E Levels and Tear Film Changes in Patients with Psoriasis Vulgaris
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Demir Helin Deniz
Aydin Erdinc
Sezer Engin
Yardim Huseyin
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Abstract
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Purpose: To evaluate whether alterations in plasma vitamin A and E levels in patients with psoriasis have an effect on tear film changes.
Methods: Sixty-two eyes of 31 patients with psoriasis vulgaris (Group A) and 74 eyes of 37 age- and gender-matched control subjects (Group B) were included in the study. Ocular and medical histories and dietary habits were obtained from each patient. The tear film break-up time (TBUT), the Schirmer 1 test results and plasma vitamin A and E levels were evaluated.
Results: The mean Schirmer 1 test score was 14.76 ± 6.12 mm/5 min in Group A and 15.69 ± 3.10 mm/5 min in Group B. The mean plasma levels of vitamins A and E in Groups A and B were 1.86 ± 0.62 μmol/L and 1.88 ± 0.65 μmol/L vs. 26.21 ± 5.13 μmol/L and 27.19 ± 8.89 μmol/L, respectively. The Schirmer 1 test results and plasma vitamin A and E levels were not found to be significantly different between the groups (p > 0.05). The mean TBUT was 9.94 ± 6.18 seconds in Group A and 14.47 ± 5.65 seconds in Group B, a significant difference (p < 0.05). No correlation existed between plasma vitamin A and E levels, TBUT or the severity and duration of the disease (p > 0.05).
Conclusions: Plasma vitamin A and E levels do not seem to be related to tear film changes in patients with psoriasis vulgaris.
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KEYWORD
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Ophthalmological diagnostic techniques, Psoriasis, Vitamin A, Vitamin E
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