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KMID : 0213520130270030167
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Korean Journal of Ophthalmology
2013 Volume.27 No. 3 p.167 ~ p.171
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The Effect of Topical Cyclosporine 0.05% on Dry Eye after Cataract Surgery
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Chung Yeon-Woong
Oh Tae-Hoon
Chung Sung-Kun
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Abstract
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Purpose: To evaluate the effectiveness of cyclosporine 0.05% for dry eye after cataract surgery.
Methods: Thirty-two newly diagnosed patients with dry eye syndrome 1 week after cataract surgery received a twice-daily treatment of cyclosporine 0.05% for one eye and normal saline 0.9% for the other. Disease severity was measured at 2 weeks, 1 month, 2 months, and 3 months by Schirmer test I (ST-I), tear film break-up time (tBUT), corneal temperature and dry eye symptom questionnaire (Ocular Surface Disease Index).
Results: Both groups increased in ST-I and tBUT over time. ST-I in the cyclosporine 0.05% group showed a significant increase at 3 months and tBUT in the cyclosporine 0.05% group showed an increase at 2 and 3 months. The dry eye symptom score was significantly reduced in the cyclosporine 0.05% group.
Conclusions: Cyclosporine 0.05% can also be an effective treatment for dry eye after cataract surgery.
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KEYWORD
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Cataract surgery, Cyclosporine, Dry eye syndromes
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