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KMID : 0213520150290030168
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Korean Journal of Ophthalmology
2015 Volume.29 No. 3 p.168 ~ p.172
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Simplified Correction of Ischemic Index in Diabetic Retinopathy Evaluated by Ultra-widefield Fluorescein Angiography
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Kim Jeong-Hee
Jung Hyeong-Gi
Chung Hye-Jin
Lee Kyung-Min
Sohn Joon-Hong
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Abstract
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Purpose: To develop a novel, simplified method for correcting the ischemic index of nonperfused areas in diabetic
retinopathy (DR).
Methods: We performed a retrospective review of 103 eyes with naive DR that underwent ultra-widefield angiography
(UWFA) over a year. UWFAs were graded according to the quantity of retinal non-perfusion, and uncorrected ischemic index (UII) and corrected ischemic index (CII) were calculated using a simplified, novel method.
Results: The average differences between UII and CII in the non-proliferative DR group and the proliferative DR group were 0.7 ± 0.9% in the <25% CII group, 3.0 ± 0.9% in the 25% to 49.9% CII group, and 3.6 ± 0.6% in the >50% CII group, respectively. A CII >25% was critical for determining DR progression (p < 0.001).
Conclusions: Distortion created by UWFA needs to be corrected because the difference between UII and CII in DR increases with the ischemic index.
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KEYWORD
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Diabetic retinopathy, Ischemic index, Wide-field fluorescein angiography
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