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KMID : 0213520160300030225
Korean Journal of Ophthalmology
2016 Volume.30 No. 3 p.225 ~ p.233
Performance of and Pressure Elevation Formed by Small-diameter Microtubes Used in Constant-flow Sets
Sohn Sae-Woon

Noh Myoung-Gyu
Lee Jong-Hyun
Kim Kyoung-Nam
Ahn Byung-Heon
Abstract
Purpose: We explored the performance of and pressure elevation caused by small-diameter microtubes used to reduce overfiltration.

Methods: Using a syringe pump-driven constant-flow setting (2 ¥ìL/min), pressures were measured for polytetrafluoroethylene (PTFE) microtubes 5 mm in length with inner diameters of 51, 64, and 76 ¥ìm and for polyether block amide (PEBAX) microtubes with an inner diameter of 76 ¥ìm. Experiments (using microtubes only) were initially performed in air, water, and enucleated pig eyes and were repeated under the same conditions using intraluminal 9/0 nylon stents.

Results: The pressures measured in air in 51-, 64-, and 76-¥ìm-diameter PTFE microtubes differed significantly (22.1, 16.9, and 12.2 mmHg, respectively; p < 0.001), and that of the 76-¥ìm-diameter PEBAX microtube was 15.8 mmHg (p < 0.001 compared to the 12.2 mmHg of the 76-¥ìm-diameter PTFE microtube). The pressures measured in water also differed significantly among the three microtubes at 3.9, 3.0, and 1.4 mmHg, respectively, while that in the PEBAX microtube was 2.6 mmHg (all p < 0.001). Using the intraluminal stent, the pressure in water of the three different PTFE microtubes increased to 22.6, 18.0, and 4.1 mmHg, respectively, and that in the PEBAX microtube increased to 10.5 mmHg (all p < 0.001). Similar trends were evident when measurements were performed in pig eyes.

Conclusions: Although microtubes of smaller diameter experienced higher pressure in air, reduction of the inner diameter to 51 ¥ìm did not adequately increase the pressure attained in water or pig eyes. Insertion of an intraluminal stent effectively elevated the latter pressures. PEBAX microtubes created higher pressures than did PTFE microtubes.
KEYWORD
Intraluminal stent, Intraocular pressure, Microtube, Polyether block amide, Polytetrafluoroethylene
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