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KMID : 0213520220360010006
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Korean Journal of Ophthalmology
2022 Volume.36 No. 1 p.6 ~ p.15
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Myopic Open-angle Glaucoma Prevalence in Northeast Asia: A Systematic Review and Meta-analysis of Population-based Studies
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Jeong Yoon
Ha Ah-Nul
Shim Sung-Ryul
Kim Young-Kook
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Abstract
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Purpose: Investigation of myopic open-angle glaucoma (OAG) prevalence in Northeast Asia by systematic review and meta-analysis.
Methods: Systematic PubMed, Embase and Cochrane database searches for Northeast Asian population-based studies published up to 30 November 2020 and reporting on myopia and OAG diagnosis. By random-effect models, pooled OAG prevalence in a myopic population and pooled myopic OAG prevalence in a general population were generated, with 95% confidence intervals (CIs).
Results: The meta-analysis encompassed five population-based studies in four countries (12,830 individuals, including 7,723 patients with myopia and 1,112 patients with OAG). In a myopic population, OAG prevalence was 4.10% (95% CI, 3.00?5.70; I2 = 93%); in a general population, myopic OAG prevalence was 1.10% (95% CI, 0.60?1.70; I2 = 94%). A visual examination of funnel plot symmetry raised a suspicion of publication bias. Notwithstanding, Begg and Mazumbar’s adjusted rank correlation test showed no such evidence (p = 0.6242).
Conclusions: Our systematic review and meta-analysis returned an estimate of OAG prevalence in a myopic Northeast Asian population. Our findings will inform future glaucoma studies as well as public health guidelines for Northeast Asian populations.
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KEYWORD
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Asia, Meta-analysis, Myopia, Open-angle glaucoma, Prevalence
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