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KMID : 0213520230370020112
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Korean Journal of Ophthalmology
2023 Volume.37 No. 2 p.112 ~ p.119
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Correlation between Interocular Asymmetry of Corneal Hysteresis and Visual Field Defect in Glaucoma
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Choi Eun-Jung
Kim Kyung-Nam
Song Mi-Yeon
Hwang Young-Hoon
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Abstract
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Purpose: To evaluate the relationship between interocular asymmetries of corneal hysteresis (CH) and visual field defects inKorean patients with glaucoma.
Methods: A total of 444 eyes from 222 participants with glaucoma in at least one eye were enrolled. CH was measured usingan ocular response analyzer (Reichert Technologies Inc). Eyes of each participant were classified into “better eye” and “worseeye” based on the mean deviation (MD) value of visual field test. The correlation between interocular differences in intraocularpressure, axial length, central corneal thickness, CH, and MD values was evaluated using Spearman correlation analysis. Toexclude the possible effect of antiglaucoma medication on corneal properties, additional analyses were performed on eyeswithout any glaucoma treatment at the time of CH measurement (treatment-naive group).
Results: Median (interquartile range) MD value was ?3.71 dB (?6.87 to ?1.30 dB) in the better eye and ?10.20 dB (?16.32 to?5.62 dB) in the worse eye. When the correlation between the asymmetry of the MD value and asymmetry of intraocularpressure, axial length, central corneal thickness, and CH were evaluated, only interocular differences in CH were significantlyassociated with interocular differences in MD values (rho = 0.214, p = 0.001). Among the 222 participants, 60 (27.0%) weretreatment-naive group. In these eyes, interocular differences in CH were also significantly associated with interocular differencesin the MD values (rho = 0.285, p = 0.029).
Conclusions: The interocular asymmetry of CH was significantly correlated with the interocular asymmetry of visual field defectsin glaucoma.
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KEYWORD
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Corneal hysteresis, Glaucoma, Visual field
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