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KMID : 0311119700110010016
Yonsei Medical Journal
1970 Volume.11 No. 1 p.16 ~ p.21
On the Effect of Morphine Hydrochloride on the Mesenteric Mast cells of Albino Rats
Park, Man Soo
Kang, Ho Suck/Pak, Soo Yun/Choi, Kum Duck
Abstract
Histological studies were carried out on the degranulation of mesenteric mast cells of white rats caused by injections of morphine and nalorphine hydrochloride intravenously and the following conclusions were obtained.
1. By the injection of morphine hydrochloride fairly significant degranulation of the mesenteric mast cell was observed.
2. In various experimental doses of morphine hydrochloride the cytological change of the degranulation was not proportional to the doses of it in cases given more than 12 mg. /kg. of body weight.
3. The degranulating effect of the mesenteric mast cell by the injection of morphine hydrochloride was significantly inhibited by an adrenalectomy.
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