|
KMID : 0311119710120010013
|
|
Yonsei Medical Journal
1971 Volume.12 No. 1 p.13 ~ p.16
|
|
|
Urea Synthesis in the Intact and in the Isolated Perfused Liver of the Biotin-Deficient Rats
|
|
Kim Je-Hyun
Cho Moo-Youn
Kim Byung-Woo
Song Chug-Suk
|
|
|
Abstract
|
|
|
Biotin-deficient rats were raised on a purified ration containing raw egg white plus avidin. Urea synthesis and excretion were compared between the biotin-deficient and the pair-fed control rats. 24hrurinary urea excretion and the specific activities of carbamylphosphate synthetase, ornithine transcarbamylase, and arginase in the liver mitochondria fraction were no different between these two groups.
The net urea production in the liver slice and in the isolated perfused liver of the biotin-deficient rats was similar to that of the pair-fed control. Thus the conclusion must be that biotin is not in urea in mea biosynthesis in the rat.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|