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KMID : 0311119990400050413
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Yonsei Medical Journal
1999 Volume.40 No. 5 p.413 ~ p.419
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Comparison of Gadomer-17 and Gd-DTPA in Image Quality of Contrast-Enhanced MR Angiographies Using Flow Phantom Model
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Byung June Jo
Tae Sub Chung/Myung Sik Lee/Jin Yang Joo†Wolfgang Ebert/Hanns-Joachim Weinmann/Daisy Chien/Gerhard Laub
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Abstract
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The purpose of this study was to compare the image quality of 3D-TOF MR angiography (MRA) using Gadomer-17 with that using Gd-DTPA in a flow phantom model, and to present preliminary data about the proper dose concentration of Gadomer-17. In the visual analysis of vessel conspicuity, we compared the quality of pre- and post-contrast MIP images. For quantitative analysis, the signal intensities were measured in the axial base 3D-TOF images, and then the relative contrast enhancement was calculated. The results of our studies were that: 1. Maximal signal intensities were obtained at 1 mmol/L of Gadomer-17 and 4 mmol/L of Gd-DTPA. 2. Flow-related signal loss was decreased by Gd-DTPA proportional to the concentration, but Gadomer-17 did not show such a dose accumulative effect. In conclusion, after comparing the results of Gd-DTPA, it was clear that improved MRA images and higher signal intensities of vessels were obtained when lower concentrations of Gadomer-17 were used.
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KEYWORD
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Magnetic resonance imaging, carotid flow phantom, magnetic resonance angiography, Gadolinium,
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