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KMID : 0311119990400060578
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Yonsei Medical Journal
1999 Volume.40 No. 6 p.578 ~ p.582
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Laparoscopic Splenectomy for Immune Thrombocytopenic Purpura -Long Term Result of 40 Laparoscopic Splenectomies-
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Woo Jung Lee/Chul Woon Chung
Woo Jung Lee/Jin Sub Choi/Yoon Woong Ko*/Ji Sook Han*/Yoo Hong Min*/Byong Ro Kim
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Abstract
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Laparoscopic surgery has recently extended its indications and it has also become an acceptable surgical approach for splenectomy. In the last five years, we have performed 40 laparoscopic splenectomies for immune thrombocytopenic purpura. Thirty-five patients were female and 5 patients were male. The mean age was 34, varying from 17 to 56. After learning to perform laparoscopic splenectomy with five ports, we are now usually using three or four ports in a right lateral kidney position. There was no case of conversion to exploratory laparotomy. The mean hospital stay was 7 days. There was no perioperative mortality; but in 2 cases we had postoperative subphrenic abscesses which were successfully managed by catheter drainage. Since undergoing laparoscopic splenectomy, 28 patients (70%) were weaned effectively from their steroid medications. Eight patients (20%) have been on small doses of steroid, and 4 patients (10%) have been on the same doses of steroid with no response. The patient group with rapidly increasing platelet count after splenectomy showed a statistically significant relation with the complete response group (p < 0.001). Laparoscopic splenectomy is a safe and reasonable operative procedure for patients with immune thrombocytopenic purpura.
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KEYWORD
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Laparoscopic surgery, splenectomy, immune thrombocytopenic purpura, hematologic disease,
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