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KMID : 0311120020430010114
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Yonsei Medical Journal
2002 Volume.43 No. 1 p.114 ~ p.118
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Acute Renal Failure Associated with a Minimal Change Nephrotic Syndrome in a Systemic Lupus Erythematosus Patient
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Moon Jae Kim/Dong Bum Seo
Seoung Woo Lee/Joon Ho Song/Kyong Joo Lee/Jee Young Han/Moon Jae Kim
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Abstract
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In systemic lupus erythematosus (SLE), acute renal failure (ARF) is usually associated with severe lupus nephritis and ARF associated with other glomerular diseases is extremely rare. We recently encountered a patient with ARF that was associated with a minimal change nephrotic syndrome (MCNS) in SLE. A 41-year-old woman presented with a nephrotic syndrome and ARF. She fulfilled four of the American College of Rheumatology criteria for the classification of SLE. However, a renal biopsy revealed that there were no glomerular abnormalities and no deposition of immune complex. The generalized edema disappeared and the high creatinine levels decreased after prednisolone therapy.
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KEYWORD
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Systemic lupus erythematosus, minimal change nephrotic syndrome, acute renal failure,
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