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KMID : 0311120070480020261
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Yonsei Medical Journal
2007 Volume.48 No. 2 p.261 ~ p.269
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Thrombosuction Utilizing an Export Aspiration Catheter during Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction
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Kang Woong-Chol
Ahn Tae-Hoon
Han Seung-Hwan
Chung Wook-Jin
Shin Mi-Seung
Koh Kwang-Kon
Choi In-Suck
Shin Eak-Kyun
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Abstract
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Purpose: Effective myocardial reperfusion after primary PCI for an AMI in lesions with a thrombus is limited by distal embolization and the slow/no reflow phenomenon. We evaluated the efficacy of a thrombus reduction technique using an export aspiration catheter for thrombosuction during primary PCI.
Materials & Methods: We analyzed 62 patients with AMIs who underwent primary PCI and had a thrombi burden during thrombosuction using an EAC (EAC group; n=31) or without thrombosuction (control group; n=31).
Results: Thrombosuction with an EAC was performed safely in all the patients in EAC group without any complications. After the PCI, restoration to a TIMI flow grade 3 was significantly more frequent in the EAC group (26/31 vs. 20/31, p < 0.05). However, the TIMI perfusion grade did not differ between the two groups. Further, the corrected TIMI frame counts were lower in the EAC group (23.9 ± 15.1 vs. 34.8 ± 22.5, p < 0.05). Although there was no statistical significance, a greater incidence of distal embolization was observed in the control group (16.1%, 5/31) as compared to the EAC group (0/31) (p= 0.056). However, the incidence of major adverse cardiac events at 1 and 6 months did not differ between the two groups.
Conclusion: For AMIs, thrombosuction with an EAC before or during PCI is a safe and potentially effective method for restoration of the coronary flow.
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KEYWORD
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Acute myocardial infarction, primary percutaneous coronary intervention, thrombosuction, export aspiration catheter
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