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KMID : 0311120070480061039
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Yonsei Medical Journal
2007 Volume.48 No. 6 p.1039 ~ p.1042
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Two Separated Ileal Adenocarcinomas in Neurofibromatosis Type 1
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Hwangbo Seal
Kim Ji-Youn
Kim Jong-Ok
Kang Chang-Suk
Lee Hye-Kyung
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Abstract
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Patients with neurofibromatosis-1 (NF-1) have increased susceptibility to a variety of malignancies. Here, we document a rare case of two separated ileal adenocarcinomas in NF-1. The adenocarcinomas were surrounded by a diffuse tubular adenomatous lesion of the mucosa, and ganglion cells were scattered in the NF background. We found this case meaningful for several reasons: two separated adenocarcinomas arising in an unusual ileal segment, the association with precancerous tubular adenoma, and the presence of ganglion cells, which suggests ganglioneuromatosis in NF-1
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KEYWORD
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Neurofibromatosis, ileum, adenocarcinoma
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