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KMID : 0311120070480061075
Yonsei Medical Journal
2007 Volume.48 No. 6 p.1075 ~ p.1078
A Case of More Abundant and Dysplastic Adenomas in the Interposed Colon than in the Native Colon
Hwang Hye-Jin

Song Kyung-Ho
Kwon Ji-Eun
Kim Ho-Guen
Lee Yong-Chan
Chung Jae-Bock
Youn Young-Hoon
Abstract
We report a 60-year-old woman with intramucosal adenocarcinoma arising in the interposed colon, 40 years after the esophageal reconstruction for lye induced esophageal stricture. Although synchronous adenomas were also found in the native colon where the graft was taken, the number of adenomas was greater in the interposed colon and more dysplastic, even progressed to adenocarcinoma, than that of the native colon. The microsatellite instability-testing performed in the intramucosal carcinoma from interposed colon showed absence of microsatellite instability. Changing of location and functional deman]d of colonic segment, and the exposure to different intraluminal contents might have facilitated the adenoma- carcinoma transformation in the interposed colon.
KEYWORD
Esophageal colon interposition, adenocarcinoma
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