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KMID : 0311120080490061052
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Yonsei Medical Journal
2008 Volume.49 No. 6 p.1052 ~ p.1054
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Gastric Schwannoma
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Yoon Ho-Young
Kim Choong-Bai
Lee Yoon-Hee
Kim Ho-Guen
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Abstract
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Schwannomas, also known as neurinomas or neurilemmomas, are generally benign, slow-growing neoplasms originating in any nerve that has a Schwann cell sheath. These neoplasms are rare among the spindle cell mesenchymal tumors of the gastrointestinal tract, but develop most commonly in the stomach representing 0.2% of all gastric tumors. We present the case of a 57-year-old female patient with a large schwannoma in the stomach that was palpable in the abdomen. She underwent subtotal gastrectomy under suspicion of gastrointestinal stromal tumor (GIST), but post-operative histopathological and immunohistochemical findings showed a fascicular arrangement of spindle cell with pallisading nuclei, and positive for S-100 protein with negative smooth muscle actin (SMA). These results confirmed schwannoma as the diagnosis.
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KEYWORD
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Schwannoma, stomach, submucosal tumor, S-100 protein
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