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KMID : 0311120100510010138
Yonsei Medical Journal
2010 Volume.51 No. 1 p.138 ~ p.140
A Case of Pathologic Splenic Rupture as the Initial Manifestation of Acute Myeloid Leukemia M2
Han Ji-Sun

Park Ki-Jae
Hong Sook-Hee
Oh Sung-Yong
Han Jin-Young
Kwon Hyuk-Chan
Kim Sung-Hyun
Kim Hyo-Jin
Abstract
A pathologic splenic rupture refers to a rupture without trauma. A splenic rupture as the initial manifestation of acute myeloid leukemia is extremely rare. In this study, we described a rare case of acute myeloid leukemia presenting principally as an acute abdomen due to a pathologic splenic rupture in a 35-year old male patient. We can assert that a pathologic splenic rupture in hematologic diseases is a potentially life-threatening complication, which necessitates immediate operative intervention. Any such patient complaining about left upper abdominal tenderness should be closely observed, and further diagnostic investigations (ultrasonograph of the abdomen, abdominal CT scan) should be initiated in order to rule out a splenic rupture. The oncologist should be aware of this rare initial presentation of acute myeloid leukemia (AML) M2, as the condition generally necessitates a prompt splenectomy.
KEYWORD
Acute myeloid leukemia M2, pathologic, splenic rupture
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