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KMID : 0311120100510030457
Yonsei Medical Journal
2010 Volume.51 No. 3 p.457 ~ p.459
Renal Stone Associated with the Ketogenic Diet in a 5-Year Old Girl with Intractable Epilepsy
Choi Ji-Na

Song Ji-Eun
Shin Jae-Il
Kim Heung-Dong
Kim Myung-Joon
Lee Jae-Seung
Abstract
In this paper, we report on a 5-year-old girl who developed a renal stone while following the ketogenic diet to treat refractory seizure disorder. Three months after initiating the ketogenic diet, she developed severe abdominal pain and vomiting. The spot urine calcium-to-creatinine (Ca/Cr) ratio and 24-hour urine evaluation showed hypercalciuria. Computed tomography (CT) imaging revealed a stone in the right ureteropelvic junction, resulting in hydronephrosis of the right kidney. The renal stone disappeared 5 days after conservative treatment; the patien¡¯s microscopic hematuria resolved concurrently. In light of this case report, we recommend regularly monitoring the urine Ca/Cr ratio with ultrasonography for further development of renal stones in patients following the ketogenic diet. If these patients exhibit evidence of symptomatic hypercalciuria or cyristalluria, liberalization of fluid restriction and urine alkalization using oral potassium citrate should be considered.
KEYWORD
Renal stone, ketogenic diet, epilepsy
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