KMID : 0311120100510040612
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Yonsei Medical Journal 2010 Volume.51 No. 4 p.612 ~ p.614
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Cutis Verticis Gyrata and Alopecia Areata: A Synchronous Coincidence?
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Yoo Kwang-Ho
Lee Jin-Woong Jang Woo-Sun Li Kap-Sok Seo Seong-Jun Hong Chang-Kwun
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Abstract
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Cutis verticis gyrata (CVG) is a descriptive term for a scalp condition that is convoluted folds and deep furrows that resemble the surface of the cerebral cortex. It is categorized by the underlying etiology, as primary essential, primary non-essential and secondary. Alopecia areata (AA) is a common, organ specific autoimmune disease, and most AA cases are sporadic. There is clearly a strong genetic component. There is no established relationship between CVG and AA. We report one case which was affected with essential primary CVG and alopecia areata, and suggest a possibility of genetic association between CVG and AA, possibly both being related to mutations in the fibroblast growth factor receptor 2 (FGFR2).
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KEYWORD
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Alopecia areata, cutis verticis gyrata, fibroblast growth factor receptor 2 (FGFR2)
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