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KMID : 0311120100510040612
Yonsei Medical Journal
2010 Volume.51 No. 4 p.612 ~ p.614
Cutis Verticis Gyrata and Alopecia Areata: A Synchronous Coincidence?
Yoo Kwang-Ho

Lee Jin-Woong
Jang Woo-Sun
Li Kap-Sok
Seo Seong-Jun
Hong Chang-Kwun
Abstract
Cutis verticis gyrata (CVG) is a descriptive term for a scalp condition that is convoluted folds and deep furrows that resemble the surface of the cerebral cortex. It is categorized by the underlying etiology, as primary essential, primary non-essential and secondary. Alopecia areata (AA) is a common, organ specific autoimmune disease, and most AA cases are sporadic. There is clearly a strong genetic component. There is no established relationship between CVG and AA. We report one case which was affected with essential primary CVG and alopecia areata, and suggest a possibility of genetic association between CVG and AA, possibly both being related to mutations in the fibroblast growth factor receptor 2 (FGFR2).
KEYWORD
Alopecia areata, cutis verticis gyrata, fibroblast growth factor receptor 2 (FGFR2)
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