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KMID : 0311120110520061025
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Yonsei Medical Journal
2011 Volume.52 No. 6 p.1025 ~ p.1027
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Fever-Induced QTc Prolongation and Ventricular Fibrillation in a Healthy Young Man
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Lim Sun-Min
Pak Hui-Nam
Lee Moon-Hyoung
Kim Sung-Soon
Joung Bo-Young
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Abstract
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Long QT syndrome is associated with lethal tachyarrhythmia that can lead to syncope, seizure, and sudden death. Congenital long QT syndrome is a genetic disorder, characterized by delayed cardiac repolarization and prolongation of the QT interval on the electrocardiogram (ECG). Type 2 congenital long QT is linked to mutations in the human ether a go-go-related gene (HERG). There are environmental triggers of adverse cardiac events such as emotional and acoustic stimuli, but fever can also be a potential trigger of life-threatening arrhythmias in long QT syndrome type 2 patients. Herein, we report a healthy young man who experienced fever-induced polymorphic ventricular tachycardia and QT interval prolongation.
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KEYWORD
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Sudden cardiac death, long QT syndrome, fever
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