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KMID : 0311120200610030257
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Yonsei Medical Journal
2020 Volume.61 No. 3 p.257 ~ p.261
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Adrenocorticotropic Hormone-Secreting Esthesioneuroblastoma with Ectopic Cushing's Syndrome
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Chung Young-Soo
Na Min-Kyun
Ku Cheol-Ryong
Kim Se-Hoon
Kim Eui-Hyun
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Abstract
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Esthesioneuroblastoma as a source of ectopic Cushing's syndrome is rare, and to the best of our knowledge, only 20 cases have been reported worldwide. A 46-year-old healthy man visited a local clinic for general weakness and hyposmia, and underwent examination with serial endocrinological workup and brain imaging. 68Gallium-DOTA-TOC positron emission tomography scan was helpful where diagnosis of sellar MRI and inferior petrosal sinus sampling were discordant. Combined transcranial and endoscopic endonasal approach surgery was performed, and a diagnosis of esthesioneuroblastoma was given.
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KEYWORD
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Cushing's disease, ectopic ACTH syndrome, esthesioneuroblastoma, positron emission tomography
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