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KMID : 0311120220630090842
Yonsei Medical Journal
2022 Volume.63 No. 9 p.842 ~ p.849
Risk Factors of Unplanned Readmission after Anterior Cervical Discectomy and Fusion: A Systematic Review and Meta-Analysis
Lee Young-Ju

Cho Pyung-Goo
Kim Keung-Nyun
Kim Sang-Hyun
Noh Sung-Hyun
Abstract
Purpose: With an increasing number of anterior cervical discectomy and fusion (ACDF) being conducted for degenerative cervical disc disease, there is a rising interest in the related quality of management and healthcare costs. Unplanned readmission after ACDF affects both the quality of management and medical expenses. This meta-analysis was performed to evaluate the risk factors of unplanned readmission after ACDF to improve the quality of management and prevent increase in healthcare costs.

Materials and Methods: We searched the databases of PubMed, EMBASE, Web of Science, and Cochrane Library to identify eligible studies using the searching terms, ¡°readmission¡± and ¡°ACDF.¡± A total of 10 studies were included.

Results: Among the demographic risk factors, older age [weighted mean difference (WMD), 3.93; 95% confidence interval (CI), 2.30?5.56; p<0.001], male [odds ratio (OR), 1.23; 95% CI, 1.10?1.36; p<0.001], and private insurance (OR, 0.34; 95% CI, 0.17?0.69; p<0.001) were significantly associated with unplanned readmission. Among patient characteristics, hypertension (HTN) (OR, 2.14; 95% CI, 1.41?3.25; p<0.001), diabetes mellitus (DM) (OR, 1.59; 95% CI, 1.20?2.11; p=0.001), coronary artery disease (CAD) (OR, 2.87; 95% CI, 2.13?3.86; p<0.001), American Society of Anesthesiologists (ASA) physical status grade >2 (OR, 2.13; 95% CI, 1.68?2.72; p<0.001), and anxiety and depression (OR, 1.39; 95% CI, 1.29?1.51; p<0.001) were significantly associated with unplanned readmission. Among the perioperative factors, pulmonary complications (OR, 22.52; 95% CI, 7.21?70.41; p<0.001) was significantly associated with unplanned readmission.

Conclusion: Male, older age, HTN, DM, CAD, ASA grade >2, anxiety and depression, pulmonary complications were significantly associated with an increased occurrence of unplanned readmission after ACDF.
KEYWORD
Anterior cervical spine surgery, readmission, risk factor, meta-analysis
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