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KMID : 0311219740050010148
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Yonsei Reports on Tropical Medicine
1974 Volume.5 No. 1 p.148 ~ p.152
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Clinical Trial of Vermox®(Mebendazole), A New Broadspectrum Anthelmintic
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Soh, Chin-Thack/蘇鎭琸
Lee, Bong-Ho/Min, Duk-Young/Chang, Soon-Ja,Lee Jae-Heung/李奉鎬/閔得映/張順子
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Abstract
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"Vermox" (generic name: Mebendazole, chemical name: Methyl 5-benzoyl-2-benzimidazole-2-carbamate) was given to the infected cases with intestinal helminths. The dosage schedule was 100 mg. b.i.d. for 3 days to the infection with Ascaris, whipworm, hookworm, Trichostrongylus and Taenia sp., and one single dose of 100 mg. to Enterobius infection. The cure rates and egg reduction rates are summarized:
Ascaris lumbricoides: 94. 0% and 99. 4%
Trichocephalus trichiurus: 85.0% and 96. 9%
Hookworms: 94. 8% and 98. 8% Trichostrongylus orientalist 95. 8% and 96.8%
Enterobius vermicularis: 90. 6% (cure rate)
Taenia sp.: 78.9% (cure rate)
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