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KMID : 0338419860010010120
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The Korean Journal of Internal Medicine
1986 Volume.1 No. 1 p.120 ~ p.125
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Postprandial 2-hr C-peptide Concentration as a Guide for Insulin Treatment in Patient with NIDDM
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:Kim Rhee-Sook
양인명:Yang In-Myung/김영설:Kim Young-Seol/김진우:Kim Jin-Woo/김광원:Kim Kwang-Won/김선우:Kim Sun-Woo/최영길:Choi Young-Kil
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Abstract
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To determine the usefulness of postpradial-2hr serum C-peptide as a guide for insulin treatment in NIDDM, the 67 NIDDM patients admitted in Kyung Hee University Hospital from Nov. 1981 to May 1984 were classified according to postprandial 2-hr insulin, C-peptide levels and 24-hr urine C-peptide levels.
The patients were divided into 3 groups according to the level of insulin or C-peptide in normal persons reported previously.9)
In 22 patients with postprandial 2-hr values of more than 5.8 ng/ml for C-peptide, 12 patients (55%) were diet controllable and only 5 patients (22%) required insulin treatment. On the other hand, in the classification according to postprandial 2-hr insulin or 24-hr urine C-peptide levels, higher response groups should be controlled by diet alone, but 9 of 18 patients (50%) for insulin, 8 of 14 patients (57%) for 24-hr urine C-peptide required insulin treatment.
The classification according to postprandial 2hr C-peptide levels was a more sensitive guide for insulin treatment than that with postprandial 2hr insulin level or 24hr urine C-peptide level.
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KEYWORD
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Postprandial 2-hr serum C-peptide, Guide for insulin treatment, NIDDM
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