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KMID : 0338419970120010080
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The Korean Journal of Internal Medicine
1997 Volume.12 No. 1 p.80 ~ p.83
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A Case of Coagulation Factor V Deficiency Complicated with Intracranial Hemorrhage
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Hee Sook Park/Suk Gu Yoon
Sung Tae Cho/Sung Kyu Park/Jong Ho Won/Seung Ho Baick/Dae Sik Hong/Hee Sook Park
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Abstract
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Factor V deficiency is a relatively uncommon disorder, inherited as an autosomal recessive trait that manifests clinically only in individuals who inherit the defective gene from both parents. The hemorrhage of nasal and oral cavity and ecchymosis are common but intracranial hemorrhage is very rare. We experienced a 53 year old male patient with intracranial hemorrhage due to factor V deficiency. The laboratory tests showed prolongation of APTT and PT, normal bleeding time and normal thrombin time. The levels of the coagulation profiles on the patient revealed a significant decrease of factor V, below 1% of normal range(60?140%). Other coagulation factors were normal. He was treated with fresh frozen plasma and completely recovered 3 weeks after treatment.
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KEYWORD
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Factor V deficiency, Intracranial hemorrhage,
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