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KMID : 0338419990140010091
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The Korean Journal of Internal Medicine
1999 Volume.14 No. 1 p.91 ~ p.94
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Successful Treatment with Ganciclovir for Cytomegalovirus Duodenitis following Allogenic Bone Marrow Transplantation
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Je Hwan Lee/Jin Hee Ahn
Je Hwan Lee/Kyoo Hyung Lee/Woo Kun Kim/Jung Shin Lee/Hye Seung Bahng/Hwoon Yong Jung/Yang Soo Kim/On ja Kim/Sang Hee Kim
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Abstract
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Cytomegalovirus (CMV) disease is a major cause of morbidity and mortality in immunocompromised patients. CMV enteritis should be considered when nausea and vomiting continue 3 to 4 weeks after bone marrow transplantation (BMT). The treatment of CMV enteritis is not well established. We report a CMV duodenitis patient following allogenic bone marrow transplantation. The patient had prolonged nausea and vomiting for 5 weeks after bone marrow transplantation and CMV duodenitis was diagnosed by the gastroduodenoscopic mucosal biopsy which showed cytomegalic cells. Ganciclovir treatment for 3 weeks resulted in the resolution of symptoms and promoted healing of the lesion. The patient was free of CMV infection until 288 days after allogenic BMT without maintenance ganciclovir treatment.
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KEYWORD
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Cytomegalovirus(CMV), BMT, Ganciclovir,
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