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KMID : 0338420000150020135
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The Korean Journal of Internal Medicine
2000 Volume.15 No. 2 p.135 ~ p.137
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Acquired hemophilia successfully treated with oral immunosuppressive therapy
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Hyeoung Joon Kim/Je Jung Lee
Ik Joo Chung/Moo Rim Park/Duc Hwan Yang/Sang Hee Cho/Dong Wook Ryang*/Hyeoung Joon Kim
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Abstract
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Acquired hemophilia is a rare disorder associated with serious bleeding in nonhemophilic patients. We had a 40-year-old woman who was diagnosed as acquired hemophilia with a factor VIII inhibitor level of 27.5 BU/mL. She was presented with gross hematuria and severe right shoulder pain, and was successfully treated with daily oral cyclophosphamide and prednisone for 2 weeks. After the remission, the doses of prednisone and cyclophosphamide were slowly decreased and she remained in complete remission without further bleeding episodes.
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KEYWORD
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Acquired hemophilia, Factor VIII inhibitor, Immunosuppressive therapy,
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