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KMID : 0338420030180010061
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The Korean Journal of Internal Medicine
2003 Volume.18 No. 1 p.61 ~ p.63
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Very Severe Aplastic Anemia appearing after Thymectomy
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Woo Sung Min/Chi Young Park
Hee Je Kim/Yoo Jin Kim/Yoon Hee Park/Jong Wook Lee/Woo Sung Min/Chun Choo Kim
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Abstract
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Aplastic anemia is a rare complication of thymoma and is extremely infrequent after thymectomy. We present a case of a 60-year-old woman with very severe aplastic anemia appearing sixteen months after thymectomy for a thymoma. She underwent thymectomy for a thymoma in April 2000. Preoperative examination revealed no hematologic abnormality. About sixteen months after the operation, she was readmitted because of pancytopenia with cough and fever. Bone marrow aspiration revealed a very severe hypoplasia in all the three cell lines with over 80% fatty tissue, and chest CT revealed no recurrence of thymoma. Her aplastic anemia had responded to cyclosporine A and granulocyte-colony stimulating factor (G-CSF).
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KEYWORD
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Aplastic anemia, Thymoma, Thymectomy, Cyclosporine A,
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