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KMID : 0338420070220010024
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The Korean Journal of Internal Medicine
2007 Volume.22 No. 1 p.24 ~ p.27
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Remission of intestinal Behcet’s disease treated with anti-tumor necrosis factor alpha monoclonal antibody (Infliximab)
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Lee Jung-Hoon
Kim Tae-Nyeun
Choi Sun-Taek
Jang Byung-Ik
Shin Kyeong-Cheol
Lee Sam-Beom
Shim Young-Ran
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Abstract
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Behcet’s disease (BD) is a chronic relapsing multisystem disease characterized by oral ulceration, genital ulceration and ocular lesions. Gastrointestinal involvement is rare, often difficult to treat and associated with a high mortality rate. We treated a 47-year-old Korean man with BD who had a recurrent intestinal ulcer with tumor necrosis factor alpha antibody (infliximab); he initially underwent right hemicolectomy due to uncontrolled intestinal bleeding. For patients with intestinal BD who fail to respond to conventional treatment, infliximab may be a safe and effective new therapeutic option.
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KEYWORD
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Behcet syndrome, tumor necrosis factor-alpha, Infliximab
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