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KMID : 0338420070220020113
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The Korean Journal of Internal Medicine
2007 Volume.22 No. 2 p.113 ~ p.117
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Castleman Disease Presenting with Jaundice: A Case with the Multicentric Hyaline Vascular Variant
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Park Jun-Bean
Hwang Jin-Hyeok
Kim Hae-Ryoung
Choe Hyung-Sim
Kim Yu-Kyeong
Kim Hong-Bin
Bang Su-Mi
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Abstract
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Castleman disease (CD) is a rare lymphoproliferative disorder of unknown etiology with different clinical manifestations. A previous healthy 50 year-old man was hospitalized for right upper quadrant (RUQ) abdominal pain. He had jaundice and a 1 cm-sized lymph node in the right supraclavicular area. Pancreas and biliary computed tomography (CT) showed masses at the right renal hilum and peripancreatic areas. Positron emission tomography (PET) showed widespread systemic lymphadenopathy. Excisional biopsy of the right supraclavicular node revealed a hyaline vascular variant of CD. Corticosteroid therapy was started and the extent of disease decreased. We here report a case of multicentric CD, the hyaline vascular variant, presenting with jaundice, diagnosed by excisional biopsy and successfully treated with corticosteroids.
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KEYWORD
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Lymphoproliferative Disorder, Jaundice, Obstructive, Castleman Disease
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