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KMID : 0338420070220030192
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The Korean Journal of Internal Medicine
2007 Volume.22 No. 3 p.192 ~ p.196
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Pulmonary Nodular Lymphoid Hyperplasia Associated with Sjogren’s Syndrome
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Song Moo-Kon
Sol Young-Mi
Park Young-Eun
Kim Yun-Seong
Lee Min-Ki
Lee Chang-Hun
Jeong Yeon-Ju
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Abstract
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Pulmonary nodular lymphoid hyperplasia (NLH) is a term first suggested by Kradin and Mark to describe one or more pulmonary nodules or localized lung infiltrates consisting of reactive lymphoid proliferation. To date, there have been only a few cases of pulmonary NLH reported associated with autoimmune disorders. There is no case of NLH associated with Sjogren’s syndrome from Korea in the medical literature. A 56-year-old woman was referred to our hospital with cough productive of sputum and chest tightness. The Computed tomography scans of the chest revealed multiple and well-defined peribronchiolar nodular opacities. A video assisted thoracoscopic surgery (VATS) biopsy was performed and the nodular opacity in the lung parenchyma was pathologically confirmed as NLH. Through meticulous review of patient’s record, we found that she had been suffering from dry eye and dry mouth. The symptoms suggested Sjogren’s syndrome, which was confirmed by specific laboratory tests including the Schirmer test,
anti-nuclear antibody and anti-Ro/La antibody. The patient is followed regularly and has no further progression of symptoms
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KEYWORD
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Pseudolymphoma, Pulmonary nodular hyperplasia, Sjogren’s syndrome
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