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KMID : 0338420080230020094
The Korean Journal of Internal Medicine
2008 Volume.23 No. 2 p.94 ~ p.99
Coagulopathy in patients who experience snakebite
Kim Jae-Seok

Yang Jae-Won
Kim Min-Soo
Han Seung-Tae
Kim Bi-Ro
Shin Myung-Sang
Lee Jong-In
Han Byoung-Geun
Choi Seung-Ok
Abstract
Background/Aims:Coagulopathy is a common complication of snakebite, but there is little information on the clinical importance of coagulopathy. We analyzed the characteristics of coagulopathy after envenomation.

Methods: Ninety-eight patients who experienced snakebite were enrolled in this study. We divided all the patients into three groups by the ISTH DIC scoring system: the normal, simple coagulopathy and DIC groups. The coagulopathy group included both the simple coagulopathy and DIC groups. We then conducted a case-control study.

Results: There was a significant decrease in the Hct, protein, albumin, ALP and cholesterol levels in the coagulopathy group, and only the cholesterol level was deceased in the DIC group (p<0.05). Leukocytosis and rhabdomyolysis were significantly associated with coagulopathy, and hemolysis and rhabdomyolysis were associated with DIC (p<0.05). The presence of rhabdomyolysis was considered a risk factor for coagulopathy (p<0.05). These conditions continued for up to six to seven days after the snakebite.

Conclusions: Evaluation of coagulopathy with using these characteristics is helpful to properly manage the patients who experience snakebite
KEYWORD
Coagulopathy, Snakebite
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