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KMID : 0338420090240040309
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The Korean Journal of Internal Medicine
2009 Volume.24 No. 4 p.309 ~ p.317
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The Prevalence of Gastrointestinal Symptoms in Patients with Non-Insulin Dependent Diabetes Mellit
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Oh Jung-Hwan
Choi Myung-Gyu
Kang Moo-Il
Lee Kang-Moon
Kim Jin-Il
Kim Byung-Wook
Lee Dong-Soo
Kim Sung-Soo
Choi Hwang
Han Sok-Won
Choi Gyu-Yong
Son Ho-Young
Chung In-Sik
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Abstract
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Background/Aims : Gastrointestinal (GI) symptoms are common among patients with non-insulin dependent
diabetes mellitus (NIDDM). Our aim was to investigate the frequency of chronic GI symptoms in Korean patients
with NIDDM.
Methods: A cross-sectional survey, using a reliable and valid questionnaire, was performed in diabetes clinics
from seven hospitals of the Catholic University of Korea.
Results: A total of 608 patients (249 males and 359 females, mean age 53.7±10.9 years) were investigated. The
frequencies of weekly heartburn and acid regurgitation (esophageal symptoms) were 7.1% (95% confidence
interval [CI], 5.0 to 9.2) and 4.4% (95% CI, 2.8 to 6.1), respectively. The frequency of dyspepsia was 13.2%
(95% CI, 10.5 to 15.8). The frequencies of constipation and diarrhea were 15.0% (95% CI, 12.2 to 18.0) and
5.3% (95% CI, 3.5 to 7.1), respectively. Nausea and the use of manual maneuvers to facilitate defecation were
more prevalent in women than in men. Constipation and fecal incontinence were more common in diabetes
patients with long duration (>10 years). Fecal incontinence and using laxatives were more frequent in the
complicated diabetes group. Using laxatives was more frequent in the uncontrolled diabetes group.
Conclusions: Two-thirds of diabetic patients experienced GI symptoms. The prevalence of GI symptoms was
more common in patients who had diabetic complications and a long duration of diabetes.
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KEYWORD
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Diabetes mellitus, type 2, Prevalence, Signs and symptoms, digestive, Diabetes complicat
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