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KMID : 0338420100250010071
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The Korean Journal of Internal Medicine
2010 Volume.25 No. 1 p.71 ~ p.76
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Ultrasonographic Features of Papillary Thyroid Carcinoma in Patients with Graves’ Disease
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Chung Jin-Ook
Cho Dong-Hyeok
Chung Dong-Jin
Chung Min-Young
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Abstract
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Background/Aims : To characterize ultrasonographic findings in papillary thyroid carcinoma (PTC) combined with Graves’ disease.
Methods: Medical records and ultrasonographic findings of 1,013 patients with Graves’ disease and 3,380 patients without Graves’ disease were analyzed retrospectively. A diagnosis of PTC was based on a pathologic examination.
Results: The frequency of hypoechogenicity was lower in patients with PTC and Graves’ disease than in patients with PTC alone (p < 0.05). The frequency of perinodular blood flow in patients with PTC and Graves’ disease was significantly higher than in those with PTC alone (p < 0.05). PTC combined with Graves’ disease was characterized by more ill-defined borders and less frequency of overall calcification, punctate calcification, and heterogeneous echogenicity, although the difference was not statistically significant.
Conclusions: Our results suggest that patients with Graves’ disease more frequently have atypical PTC findings on ultrasonography.
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KEYWORD
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Graves disease, Thyroid neoplasms, Ultrasonography
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