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KMID : 0338420130280040475
The Korean Journal of Internal Medicine
2013 Volume.28 No. 4 p.475 ~ p.480
Malakoplakia in a healthy young female patient
Hyun Kyung-Hee

Shin Hyun-Deok
Kim Dong-Hoon
Abstract
Malakoplakia is a rare granulomatous disease that occurs commonly in the urinary tract and secondarily in the gastrointestinal tract. Most reported cases of malakoplakia are associated with immunosuppressive diseases or chronic prolonged illness. Here, we report a rare case of malakoplakia in a young healthy adolescent without any underlying disease. A 19-year-old female was referred to our hospital following the discovery of multiple rectal polyps with sigmoidoscopy. She had no specific past medical history but complained of recurrent abdominal pain and diarrhea for 3 months. A colonoscopy revealed diverse mucosal lesions including plaques, polyps, nodules, and mass-like lesions. Histological examination revealed a sheet of histiocytes with pathognomonic Michaelis-Gutmann bodies. We treated the patient with ciprofloxacin, the cholinergic agonist bethanechol, and a multivitamin for 6 months. A follow-up colonoscopy revealed that her condition was resolved with this course of treatment.
KEYWORD
Malakoplakia, Michaelis-Gutmann bodies, Diverse mucosal lesions
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