|
KMID : 0338420130280060660
|
|
The Korean Journal of Internal Medicine
2013 Volume.28 No. 6 p.660 ~ p.667
|
|
|
The diagnostic efficacy and safety of endobronchial ultrasound-guided transbronchial needle aspiration as an initial diagnostic tool
|
|
Choi Young-Rak
An Jin-Young
Kim Mi-Kyeong
Han Hye-Suk
Lee Ki-Hyeong
Kim Si-Wook
Lee Ki-Man
Choe Kang-Hyeon
|
|
|
Abstract
|
|
|
Background/Aims: Real-time, convex probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is used for the staging of malignant mediastinal lymph nodes. We evaluated the diagnostic efficacy and safety of EBUS-TBNA when used as an initial diagnostic tool.
Methods: We retrospectively studied 56 patients who underwent EBUS-TBNA as an initial diagnostic tool between August 2010 and December 2011. Procedure purpose were classified into four categories: 1) intrathoracic masses adjacent to the central airway; 2) enlarged lymph nodes for concurrent diagnosis and staging in suspected malignancy; 3) enlarged lymph nodes in suspected malignancy cases with inability to perform percutaneous core needle biopsy (PCNB); and 4) solely mediastinal masses/lymph nodes in lieu of mediastinoscopy.
Results: The diagnostic accuracy of EBUS-TBNA regardless of procedure purpose was calculated to be 83.9%. Furthermore, the diagnostic accuracy of malignant disease was significantly higher than benign disease (93.9% vs. 70.6%, p < 0.001). The diagnostic accuracy of EBUS-TBNA for each disease is as follows: tuberculosis, 50%; sarcoidosis, 60%; aspergillosis, 100%; lung abscess, 100%; lung cancer, 93%; and lymphoma, 100%. There were minor complications in seven patients during the EBUS-TBNA procedure. The complications included mild hypoxia and bleeding.
Conclusions: In conclusion, EBUS-TBNA is a useful initial diagnostic tool for both benign and malignant diseases. EBUS-TBAN is also a very safe procedure and less invasive compared to mediastinoscopy or PCNB.
|
|
|
KEYWORD
|
|
|
Endobronchial ultrasound-guided transbronchial needle aspiration, Mediastinal mass, Intrathoracic mass
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
    
|