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KMID : 0338420130280060728
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The Korean Journal of Internal Medicine
2013 Volume.28 No. 6 p.728 ~ p.731
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A case of Tsutsugamushi disease presenting with nephrotic syndrome
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Lee Ju-Hyun
Lee Mi-Jung
Shin Dong-Ho
Kang Shin-Wook
Choi Kyu-Hun
Yoo Tae-Hyun
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Abstract
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Nephrotic syndrome associated with Tsutsugamushi disease has not been previously reported. We are describing a case of Tsutsugamuchi disease presenting with nephrotic syndrome. A 72-year-old woman presented with fever and generalized edema. Laboratory studies revealed a leukocytosis, hypoalbuminemia, and hypercholesterolemia. Her urine protein excretion was 5.4 g/day. The anti-Tsutsugamushi antibody test was strongly positive (1:2,560). A renal biopsy was performed, and pathologic findings revealed membranous glomerulonephritis. The patient’s clinical symptoms improved markedly after treatment with doxycycline.
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KEYWORD
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Nephrotic syndrome, Scrub typhus, Glomerulonephritis, Membranous
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