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KMID : 0338420140290020236
The Korean Journal of Internal Medicine
2014 Volume.29 No. 2 p.236 ~ p.240
Hypersensitivity myocarditis confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy
Park Yu-Mi

Ahn Sung-Gyun
Ko An-Na
Ra Sang-Ho
Cha Jae-Hwang
Jee Yong-Gwan
Lee Ji-Hyun
Abstract
Myocarditis often occurs due to viral infections and postviral immune-mediated responses. Hypersensitivity myocarditis is a rare form of myocarditis. Numerous drugs can induce myocarditis, which is typically reversible after withdrawal of the causative agent. Here, we report a case of hypersensitivity myocarditis that was probably triggered by amoxicillin and that resolved completely with heart failure management as well as discontinuation of the drug. A 68-year-old woman presented with acute chest pain mimicking acute coronary syndromes, but the coronary angiography was normal. A recent history of taking medications, skin rash, and peripheral eosinophilia suggested a diagnosis of hypersensitivity myocarditis, which was confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy.
KEYWORD
Myocarditis, Drug hypersensitivity, Magnetic resonance imaging, Biopsy
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