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KMID : 0338420140290060764
The Korean Journal of Internal Medicine
2014 Volume.29 No. 6 p.764 ~ p.773
Disease burden of pneumonia in Korean adults aged over 50 years stratified by age and underlying diseases
Lee Jung-Yeon

Yoo Chul-Gyu
Kim Hyo-Jin
Jung Ki-Suck
Yoo Kwang-Ha
Abstract
Background/Aims: This study was conducted to assess the disease burden of pneumonia according to age and presence of underlying diseases in patients admitted with community-acquired pneumonia (CAP).

Methods: We performed a retrospective, observational study and collected data targeting patients with CAP (¡Ã 50 years) from 11 hospitals. Disease burden was defined as total per-capita medical fee, severity (CURB-65), hospital length of stay (LOS), and mortality.

Results: Of the 693 enrolled subjects, elderly subjects (age, ¡Ã 65 years) had a higher mean CURB-65 score (1.56 vs. 0.25; p < 0.01) and higher mortality than nonelderly subjects (4.4% [n = 21] vs. 0.5% [n = 1]; p = 0.00). In addition, the total cost of pneumonia treatment was higher in elderly patients compared to in nonelderly patients (KRW 2,088,190 vs. US $1,701,386; p < 0.01). Those with an underlying disease had a higher CURB-65 score (1.26 vs. 0.68; p < 0.01), were much older (mean age, 71.24 years vs. 64.24 years; p < 0.01), and had a higher mortality rate than those without an underlying disease (3.5% [n = 20] vs. 1.7% [n = 2]; p = 0.56). Total per-capita medical fees were higher (KRW 2,074,520 vs. US $1,440,471; p < 0.01) and hospital LOS was longer (mean, 8.38 days vs. 6.42 days; p < 0.01) in patients with underlying diseases compared to those without.

Conclusions: Due to the relatively high disease burden in Korea, particularly in the elderly and in those with an underlying disease, closer and more careful observation is needed to improve the outcomes of patients with CAP.
KEYWORD
Pneumonia, Costs and cost analysis, Comorbidity, Age factors
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