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KMID : 0338420150300020205
The Korean Journal of Internal Medicine
2015 Volume.30 No. 2 p.205 ~ p.211
Relationship between duration of hospital-acquired acute kidney injury and mortality: a prospective observational study
:Yoo Jin-Young
:Lee Ji-Sung/:Lee Ji-Yeon/:Jeon Jin-Seok/:Noh Hyun-Jin/:Han Dong-Cheol/:Kwon Soon-Hyo
Abstract
Background/Aims: New definitions of acute kidney injury (AKI) have recently emerged. Some studies have suggested that duration of AKI is an additional predictive parameter for mortality. Here, we evaluated whether AKI duration was predictive of long-term mortality in patients with hospital-acquired acute kidney injury (HAAKI).

Methods: We prospectively enrolled patients who developed HAAKI at an urban university hospital, from September 2007 to August 2008 and followed them until December 2011. Patients were divided into two groups by duration of the AKI (1 to 5 days vs. ¡Ã 6 days), and long-term mortality was compared.

Results: HAAKI developed in 1.2% of patients during the enrollment period. The median follow-up period was 240 days (interquartile range, 53 to 1,428). In 42.3% of patients (n = 52), the AKI lasted 1 to 5 days, while it lasted ¡Ã 6 days in 57.7% (n = 71). Survival analysis showed that a longer duration of AKI increased the risk of death. Long-term survival was significantly different in the two groups.

Conclusions: The duration of AKI influenced mortality rates in hospitalized patients. Thus, AKI duration is a parameter affecting mortality in HAAKI.
KEYWORD
Acute kidney injury, Duration, Mortality, Recovery, Survival
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