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KMID : 0338420240390010184
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The Korean Journal of Internal Medicine
2024 Volume.39 No. 1 p.184 ~ p.193
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Characteristics of patients with psoriatic arthritis in Korea: focusing on axial involvement
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Park Han-Na
Lee Ji-Hyun
Kwok Seung-Ki
Ju Ji-Hyeon
Kim Wan-Uk
Park Sung-Hwan
Lee Joo-Ha Jennifer
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Abstract
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Background/Aims: We aimed to clarify the clinical characteristics of psoriatic arthritis (PsA) in Korean patients focusing on PsA with axial involvement.
Methods: A retrospective medical chart review was performed to identify PsA patients at a single tertiary center. Cases of AS patients with psoriasis were recruited from a prospective AS registry of the same center. Demographics, laboratory findings, and radiologic characteristics were assessed.
Results: A total of 69 PsA patients were identified. In PsA patients, spondylitis (46.4%) was the most common form. Compared to AS patients with psoriasis, PsA patients with radiographic axial involvement were older (50.9 vs. 32.4 years; p < 0.001) and showed greater peripheral disease activity (peripheral arthritis 78.1 vs. 12.5%, p < 0.001; enthesitis 50.0 vs. 6.3%, p = 0.003). AS patients with psoriasis presented a higher rate of HLA-B*27 positivity (81.3 vs. 17.2%; p < 0.001) and a more frequent history of inflammatory back pain (100.0 vs. 75.0%; p = 0.039) than PsA patients with radiographic axial involvement.
Significant proportions of PsA patients with radiographic axial involvement had cervical spine involvement (10/18, 55.6%) reacand spondylitis without sacroiliitis (10/23, 43.5%).
Conclusions: We demonstrate that axial involvement is common in Korean PsA patients, and its characteristics can be distinct from those of AS.
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KEYWORD
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Psoriatic arthritis, Ankylosing spondylitis, Sacroiliitis, Osteophyte
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