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KMID : 0357920000340010096
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Korean Journal of Pathology
2000 Volume.34 No. 1 p.96 ~ p.98
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Myofibrosarcoma of the Breast -A case report-
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Jung Chan-Kwon
Lee Kyo-Young
Kang Chang-Suk
Shim Sang-In
Kim Byung-Kee
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Abstract
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Myofibrosarcoma of the breast is a rare malignant mesenchymal tumor that has been reported in only four well documented cases so far. We report a case of myofibrosarcoma of the breast in an 88-year-old man who complained of a palpable mass for 1 year. Microscopically, the tumor consisted mainly of spindled cells, arranged in irregular fascicles and embedded in broad bands of dense hyalinized collagen. It showed ill-defined border infiltrating the adjacent adipose tissue, moderate cellular pleomorphism, and high mitotic rate (8∼9/10 HPF). Immunohistochemical study confirmed myofibroblastic differentiation of the tumor cells with diffuse strong reaction for vimentin, smooth muscle actin, and fibronectin.
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KEYWORD
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Myofibrosarcoma, Breast
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